This invention describes a testing cartridge designed to quickly and accurately find tiny targets like cells or viruses in samples. It works by guiding the sample through a series of wells, including one for growth with antibiotics, to an imaging area, using special signaling and selection chemicals along with a dense dye cushion to simplify the process and avoid washing steps. The cartridge is specifically designed to use a density agent, such as sugar or salt solutions, as the dye cushion.
Why it matters: Since 2019, the widespread integration of high-resolution cameras into consumer devices and advancements in microfluidic fabrication have lowered the barrier for producing such integrated diagnostic cartridges. This makes the "low magnification" imaging and complex fluidic design more accessible.
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