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Patent drawing for Use of vibrational spectroscopy for DNA content inspection
US 10,175,159 B2
Materials testing US 10,175,159 B2 Not in force

Use of vibrational spectroscopy for DNA content inspection

This invention describes a system that uses a laser to shine light on individual cells flowing through a tiny channel. The laser makes the DNA inside the cell vibrate, and the system then detects these unique vibrations. By analyzing these vibrations, it can figure out how the DNA is folded or packed, specifically designed for unstained sperm cells.

Why it matters: Advancements in label-free single-cell analysis and spectroscopic sensitivity over the past decade could make this approach more practical. The ability to analyze unstained cells, especially sperm, has become increasingly valuable in reproductive health and research.

Status
Not in forceListed as no longer active. The specific reason is not in the record we hold.
How hard to build
SpecializedMicrofluidics, precision optics, sensitive spectroscopy, software

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