This invention describes a small, rod-shaped device designed to be implanted under the skin for long-term drug delivery. It has a core made of a common plastic called EVA, which doesn't contain any medicine. This core is then surrounded by layers that contain specific thyroid hormones, L-triiodothyronine and/or L-thyroxine, which are slowly released into the body over an extended period.
Why it matters: Since 2013, the growing emphasis on patient adherence and stable therapeutic drug levels for chronic conditions has increased the clinical and commercial viability of long-acting implantable drug delivery systems.
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